Developmental Toxicity of the Neural Tube Induced by Titanium Dioxide Nanoparticles

Developmental Toxicity of the Neural Tube Induced by Titanium Dioxide Nanoparticles

Developmental Toxicity of the Neural Tube Induced by Titanium Dioxide Nanoparticles in Mouse Embryos

Background: This research investigated the potential results of Titanium dioxide nanoparticles (Tio2NPs) adopted by maternal gavage on fetal growth and neural tube formation throughout being pregnant in mice.

Strategies: Thirty pregnant mice have been randomly divided into 5 fundamental research teams together with the untreated management and Four experimental teams (n=6 per group). The management group was handled with regular saline and the experimental teams have been orally handled with doses of 30, 150, 300, and 500 mg/kg Physique Weight (BW) of Tio2NPs throughout being pregnant. On gestational day 16 and 19 (n=three per group), pregnant mice have been euthanized after which examined for neural tube defects and in contrast with management. Serial transverse sections have been ready in each cranial area and in lumbar area of spinal twine.

Outcomes: Therapy with Tio2NPs resulted in low fetal weight and brief size, dilation of lateral ventricle, thinning of cerebral cortex and spinal twine, spina bifida occulta and a rise within the variety of apoptotic neurons in uncovered embryos at doses of 300 and 500 mg/kg (p<0.05).

Conclusion: It appears that evidently publicity to nanoparticles of Tio2 throughout being pregnant induces progress retardation and for the primary time, teratogenicity of this nanomaterial in neural tube growth and induction of defects equivalent to spinal bifida, discount in cortical thickness and dilatation of lateral ventricles have been verified which might be associated to incidence of apoptosis in central nervous system.

Software of Omaha system-based persevering with care in sufferers with retained double J tube after urinary calculus surgical procedure

Goal: To discover the impact of Omaha system-based persevering with care in sufferers with retained double J tube after urinary calculus surgical procedure.

Strategies: A complete of 124 sufferers hospitalized with retained double J ureteral stent after urinary calculus surgical procedure have been chosen because the analysis topics. In response to the random quantity desk technique, they have been divided into statement group (n=62) and management group (n=62). The management group was given common persevering with care, whereas the statement group was given the Omaha system-based persevering with care. Consciousness of information relating to retained double J tube, anxiousness, melancholy, sleep high quality, high quality of life, incidence of problems, and affected person satisfaction have been in contrast between the 2 teams.

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Axygen 0.2ml thin walled flat cap PCR tube red

AXY2056 PK1000
EUR 79.2

Axygen 0.2ml thin walled flat cap PCR tube blue

AXY2020 PK1000
EUR 79.2

Axygen 0.5ml thin walled flat cap PCR tube blue

AXY2066 PK1000
EUR 67.2

Axygen 0.2ml thin walled flat cap PCR tube green

AXY2048 PK1000
EUR 79.2

Axygen 0.2ml thin walled flat cap PCR tube violet

AXY2060 PK1000
EUR 79.2

Axygen 0.2ml thin walled flat cap PCR tube yellow

AXY2062 PK1000
EUR 79.2

Axygen 0.5ml thin walled flat cap PCR tube violet

AXY2076 PK1000
EUR 67.2

PCR-Tubes 0,2 ml flat cap (transparent, thin walled)

A22203 2x1000 pcs
EUR 99.6

Axygen 0.2ml MaxyClear thin walled flat cap PCR tube

AXY2022 PK1000
EUR 76.8

Axygen 0.5ml MaxyClear thin walled flat cap PCR tube

AXY2068 PK1000
EUR 64.8

Axygen 0.2ml MaxyClear thin walled domed cap PCR tube

AXY2030 PK1000
EUR 76.8

Axygen 0.2ml thin walled flat cap PCR tube assorted colours

AXY2018 PK1000
EUR 81.6

Axygen 0.5ml thin walled flat cap PCR tube assorted colours

AXY2064 PK1000
EUR 68.4

Axygen 0.2ml thin walled domed cap PCR tube assorted colours

AXY20260 PK10000
EUR 781.2

Axygen 0.2ml MaxyClear thin walled PCR tube strip 8 per strip

AXY2014 PK125
EUR 148.8

Axygen 0.2ml MaxyClear thin walled PCR caps for qPCR 8 per strip

AXY2080 PK125
EUR 50.4

Axygen 0.2ml MaxyClear thin walled flat cap Maxymum Recovery PCR tube

AXY2050 PK1000
EUR 108

Axygen 0.2ml MaxyClear thin walled domed cap Maxymum Recovery PCR tube

AXY2034 PK1000
EUR 108

Axygen 0.2ml MaxyClear thin walled without cap Maxymum Recovery PCR tube

AXY2052 PK1000
EUR 76.8

Carbon Steel Scalpel Blades 11

43230001-1 1 PK(s)
EUR 19.04

Axygen 0.2ml MaxyClear thin walled PCR tubes with domed caps 8 per strip

AXY2016 PK125
EUR 157.2

Type IX Collagen Staining Kit, Multi-Species

9012 1 kit
EUR 406.26
Description: Type IX Collagen Staining Kit

Type II Collagen Detection Kit, Multi-Species

6018 1 kit
EUR 808.2
Description: Type II Collagen Detection Kit

Carbon Powder

CARB-10 10
EUR 17
Description: Carbon powder used for preparation of urine samples for use with the Oxalate Quick Test Strips. Quantity: 10 tubes of 50 mg carbon powder.

Carbon disulfide

S-745 1ML
EUR 45.6

Carbon tetrachloride

S-750 1ML
EUR 45.6

isa carbon dioxide

ISA51 ea
EUR 109.2

CHLOROMETHYL ISOPROPYL CARBONATE (CARBON)

603001 each Ask for price

carbon dioxide electrode

ISE51B ea
EUR 534

Suez C350 Carbon Cartridge

WAT3306 EACH
EUR 142.8

Suez C750 Carbon Cartridge

WAT3308 EACH
EUR 219.6

cal. solution carbon dioxide

ISC51 ea
EUR 109.2

ICP Multi Elem (11) Std in 2% HCl

ICP11-MIX-100 100ML
EUR 569.24

VOC Carbon Tetrachloride Neat

REVOC111N 10MG
EUR 46.87

4 X 10 CARBON CARTRIDGE

CDFC410F2 EACH
EUR 398.21

4 X 20 CARBON CARTRIDGE

CDFC420F2 EACH
EUR 740.28

ICP Std Carbon 1000ug/mL in H2O

PC2A7 100ML
EUR 136.8

ICP Std Carbon 1000ug/mL in H2O

PC2B7 250ML
EUR 236.31

ICP Std Carbon 10000ug/mL in H2O

PC4B7 250ML
EUR 355.12

Carbon AEF for 0.9m Cabinet

CAB2726 EACH
EUR 2743.2

Carbon AEF for 1.8m Cabinet

CAB2730 EACH
EUR 2538

ICP Multi Elem (11) Effluent Std No.2

STD11-EFF2-500 500ML
EUR 489.6

CARBON CART. 12 IN 4/PK

CDFC01204 EACH
EUR 832.97

CARBON CART 22 IN 3/PK

CDFC02203 EACH
EUR 1022.28

Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) ELISA Kit

SEG945Mi-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) ELISA Kit

SEG945Mi-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) ELISA Kit

SEG945Mi-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) ELISA Kit

SEG945Mi-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) ELISA Kit

4-SEG945Mi
  • EUR 5895.60
  • EUR 3114.00
  • EUR 786.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Multi-species Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

F13S - 14x50c Carbon Fiber Rotor

75003661 EACH
EUR 5985.6

Carbon Steel Scalpel Blades 10

43230000-1 1 PK(s)
EUR 19.04

Carbon Steel Scalpel Blades 15

43230002-1 1 PK(s)
EUR 19.04

Carbon Steel Scalpel Blades 20

43230003-1 1 PK(s)
EUR 19.04

Carbon Steel Scalpel Blades 21

43230004-1 1 PK(s)
EUR 19.04

Carbon Steel Scalpel Blades 22

43230005-1 1 PK(s)
EUR 23.83

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-601)

GX0759-100 100
EUR 228.1

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-601)

GX0759-50 50
EUR 163

Scalpel Blade Carbon Steel No10

INS4610 PK100
EUR 31.2

Scalpel Blade Carbon Steel No11

INS4614 PK100
EUR 31.2

Scalpel Blade Carbon Steel No12

INS4616 PK100
EUR 31.2

Scalpel Blade Carbon Steel No15

INS4618 PK100
EUR 31.2

Scalpel Blade Carbon Steel No20

INS4620 PK100
EUR 34.8

Scalpel Blade Carbon Steel No21

INS4622 PK100
EUR 34.8

Scalpel Blade Carbon Steel No22

INS4624 PK100
EUR 34.8

Scalpel Blade Carbon Steel No23

INS4628 PK100
EUR 34.8

Scalpel Blade Carbon Steel No24

INS4630 PK100
EUR 34.8

Scalpel Blade Carbon Steel No25

INS4632 PK100
EUR 34.8

Scalpel Blade Carbon Steel No26

INS4634 PK100
EUR 34.8

Scalpel Blade Carbon Steel No27

INS4636 PK100
EUR 34.8

Activated carbon, granules 2.5 mm

GX9755-1 1
EUR 226.6

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0602)

GX6147-100 100
EUR 228.1

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0602)

GX6147-50 50
EUR 163

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0604)

GX6637-100 100
EUR 228.1

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0604)

GX6637-50 50
EUR 163

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0603)

GX7358-100 100
EUR 228.1

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0603)

GX7358-50 50
EUR 163

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0605)

GX7518-100 100
EUR 228.1

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0605)

GX7518-50 50
EUR 163

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0609)

GX9801-100 100
EUR 228.1

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0609)

GX9801-50 50
EUR 163

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0607)

GX3267-100 100
EUR 228.1

Silver on Activated Carbon 0,5% Ag/C (Heraeus-Type K-0607)

GX3267-50 50
EUR 163

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0608)

GX3306-100 100
EUR 228.1

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0608)

GX3306-50 50
EUR 163

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0606)

GX0072-100 100
EUR 228.1

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0606)

GX0072-50 50
EUR 163

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0600)

GX1516-100 100
EUR 228.1

Silver on Activated Carbon 0,3% Ag/C (Heraeus-Type K-0600)

GX1516-50 50
EUR 163

Scalpel Blade Carbon Steel No10A

INS4612 PK100
EUR 31.2

Scalpel Blade Carbon Steel No22A

INS4626 PK100
EUR 34.8

Rhodium on Activated Carbon 5% Rh/C (Heraeus-Type K-0312)

GX4664-5 5
EUR 163

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0124)

GX4727-10 10
EUR 143.2

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0124)

GX4727-50 50
EUR 368.2

Platinum on Activated Carbon 10% Pt/C (Heraeus-Type K-0119)

GX5558-10 10
EUR 179.3

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0127)

GX5652-10 10
EUR 143.2

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0127)

GX5652-5 5
EUR 113.1

Platinum on Activated Carbon 1% Pt/C (Heraeus-Type K-0117)

GX6364-10 10
EUR 128.1

Platinum on Activated Carbon 1% Pt/C (Heraeus-Type K-0117)

GX6364-100 100
EUR 466

Platinum on Activated Carbon 1% Pt/C (Heraeus-Type K-0117)

GX6364-50 50
EUR 319.4

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0125)

GX6563-10 10
EUR 143.2

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0125)

GX6563-50 50
EUR 358.4

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0130)

GX7784-10 10
EUR 135.6

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0130)

GX7784-5 5
EUR 105.5

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0130)

GX7784-50 50
EUR 344

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0129)

GX8533-10 10
EUR 143.2

Platinum on Activated Carbon 5% Pt/C (Heraeus-Type K-0129)

GX8533-50 50
EUR 368.2

Platinum on Activated Carbon 1% Pt/C (Heraeus-Type K-0114)

GX8702-100 100
EUR 466

Platinum on Activated Carbon 1% Pt/C (Heraeus-Type K-0114)

GX8702-50 50
EUR 319.4

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0132)

GX2268-10 10
EUR 135.6

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0132)

GX2268-5 5
EUR 105.5

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0132)

GX2268-50 50
EUR 344

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0131)

GX2396-10 10
EUR 135.6

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0131)

GX2396-5 5
EUR 105.5

Platinum on Activated Carbon 2% Pt/C (Heraeus-Type K-0131)

GX2396-50 50
EUR 344

Carbon AEF for 1.2/1.5m Cabinet

CAB2728 EACH
EUR 2628

ICP Multi Elem (11) Verif Std in 5% HNO3

REICPVER11A 100ML
EUR 637.13

Palladium on Activated Carbon 1% Pd/C (Heraeus-Type K-0236)

GX4532-10 10
EUR 98

Palladium on Activated Carbon 1% Pd/C (Heraeus-Type K-0236)

GX4532-50 50
EUR 220.1

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0209)

GX5650-10 10
EUR 113.1

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0209)

GX5650-50 50
EUR 270.4

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0224)

GX6197-10 10
EUR 105.5

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0224)

GX6197-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0224)

GX6197-50 50
EUR 244.3

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0259)

GX6502-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0259)

GX6502-50 50
EUR 244.3

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0261)

GX7259-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0261)

GX7259-50 50
EUR 244.3

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0227)

GX8277-10 10
EUR 113.1

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0227)

GX8277-5 5
EUR 90.4

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0227)

GX8277-50 50
EUR 270.4

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0201)

GX8667-10 10
EUR 113.1

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0257)

GX2409-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0257)

GX2409-50 50
EUR 244.3

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0261)

GX0043-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0261)

GX0043-50 50
EUR 244.3

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0258)

GX0299-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0258)

GX0299-50 50
EUR 244.3

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0255)

GX0791-10 10
EUR 105.5

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0255)

GX0791-100 100
EUR 344

Palladium on Activated Carbon 3% Pd/C (Heraeus-Type K-0255)

GX0791-50 50
EUR 244.3

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0219)

GX0848-10 10
EUR 113.1

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0219)

GX0848-5 5
EUR 90.4

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0219)

GX0848-50 50
EUR 270.4

Palladium on Activated Carbon 5% Pd/C (Heraeus-Type K-0201S)

GX3964-5 5
EUR 90.4

ICP Multi Elem (11) Effluent Std in 5% HCl

STD11-EFF3-500 500ML
EUR 408.65

Whatman Vacu Guard 150 Carbon PTFE

FIL5174 PK10
EUR 194.4

Carbon Disulphide, GlenDry™, anhydrous

GS7652-100 100
EUR 152.7

Carbon Disulphide, GlenDry™, anhydrous

GS7652-500 500
EUR 500.6

Grids - Carbon Coated - Copper 200 mesh

24918-25 25EA
EUR 158

Grids - Carbon Coated - Copper 200 mesh

24918-50 50EA
EUR 161

Grids - Carbon Coated - Copper 300 mesh

24933-25 25EA
EUR 158

Grids - Carbon Coated - Copper 300 mesh

24933-50 50EA
EUR 269

Grids - Carbon Coated - Copper 400 mesh

24948-100 100EA
EUR 569

Grids - Carbon Coated - Copper 400 mesh

24948-25 25EA
EUR 154

Grids - Carbon Coated - Copper 400 mesh

24948-50 50EA
EUR 285

Razor Cut Throat Carbon Steel Blade

INS4500 EACH
EUR 30

ICP Multi Elem (11) Std in 5% HNO3 1000mg/L

REICP11MIX4A 100ML
EUR 439.99

ICP Multi Elem (11) Std in 2% HNO3 1000mg/L

REICPCAL11U 500ML
EUR 876.06

EP Reagent Carbon Dioxide Free Water

1095502 1L
EUR 76.8

EP Reagent Carbon Dioxide Free Water

1095502TO 1L
EUR 124.03

Whatman Carbon Cap 75 Capsule Filter

FIL5300 EACH
EUR 192

Whatman Carbon Cap 150 Capsule Filter

FIL5302 EACH
EUR 162

WHATMAN(TM) CARBON/HEPA FILTER CAPSULE

WHA67041500 EACH
EUR 170.4

Activated carbon, powder max. 100 micron

GX2452-1 1
EUR 283.5

ICP Multi Elem (11) Interf Std in 2-5% HNO3

REICPINTF11A 100ML
EUR 612.33

 

Prediction of velocity profile of water primarily based copper nanofluid in a heated porous tube utilizing CFD and genetic algorithm

The warmth switch enhancements by simultaneous utilization of the nanofluids and metallic porous foams are nonetheless a pretty analysis space. The Computational fluid dynamics (CFD) strategies are broadly used for thermal and hydrodynamic investigations of the nanofluids circulation contained in the porous media. Virtually all research devoted to the correct prediction of the CFD method. Nonetheless, there are usually not enough investigations on the CFD method optimization. The mesh increment within the CFD method is likely one of the difficult ideas particularly in turbulent flows and sophisticated geometries.

This research, for the primary time, introduces a sort of synthetic intelligence algorithm (AIA) as a supplementary instrument for serving to the CFD. In response to the concept of this research, the CFD simulation is finished for a case with low mesh density. The synthetic intelligence algorithm makes use of learns the CFD pushed knowledge. After the intelligence achievement, the AIA may predict the fluid parameters for the infinite variety of nodes or dense mesh with none limitations. So, there isn’t a want to resolve the CFD fashions for additional nodes. This research is particularly targeted on the genetic algorithm-based fuzzy inference system (GAFIS) to foretell the rate profile of the water-based copper nanofluid turbulent circulation in a porous tube. Essentially the most clever GAFIS may carry out essentially the most correct prediction of the rate.

Therefore, the intelligence of GAFIS is examined for various values of cluster affect vary (CIR), squash issue(SF), settle for ratio (AR) and reject ratio (RR), the inhabitants dimension (PS), and the proportion of crossover (PC). The utmost coefficient of willpower (~ 0.97) was associated to the PS of 30, the AR of 0.6, the PC of 0.4, CIR of 0.15, the SF 1.15, and the RR of 0.05. The GAFIS prediction of the fluid velocity was in nice settlement with the CFD. In essentially the most clever situation, the rate profile predicted by GAFIS was much like the CFD. The nodes increment from 537 to 7671 was made by the GAFIS. The brand new predictions of the GAFIS coated all CFD outcomes.

The VANGL1 P384R variant trigger each neural tube defect and Klippel-Feil syndrome

Background: Neural tube defect (NTD) is a typical beginning defect inflicting a lot dying on this planet. Variants in VANGL1 result in NTD and caudal regression syndrome. NTD shows a fancy phenotype encompassing each genetic and environmental elements.

Strategies: The fetus was recognized by prenatal ultrasound examination. Postnatal CT and post-mortem have been carried out. Genetic testing was carried out within the household and Sanger sequencing was validated. A number of prediction soft-wares have been used to foretell the pathogenicity of the variant.

Outcomes: The VANGL1 gene variant c.1151C>G (P384R) was detected in a fetus recognized with tethered spinal twine and sacrococcygeal lipoma. The VANGL1 variant c.1151C>G (P384R) was reported in a Klippel-Feil syndrome affected person. The VANGL1 variant was validated within the trio-family however the mom confirmed no abnormalities.

Conclusion: General, this research presents fetal NTD brought on by the identical VANGL1 variant present in a Klippel-Feil syndrome affected person with full scientific info of prenatal ultrasound, postnatal CT, and genetic outcomes as early as 25 GW. Our research not solely expands the VANGL1 mutational spectrum but in addition sheds mild on the vital function of the VANGL1 P384R variant in human growth.

MTHFR C677T and A1298C variants in Mexican Mestizo infants with neural tube defects from Western Mexico

Our research investigated the function of MTHFR C677T and A1298C variants in infants with neural tube defects (NTDs) from western Mexico. Utilizing TaqMan allelic discrimination assay, we genotyped 101 live-born sufferers with NTDs (instances) and 247 controls. Our findings don’t help that homozygosity or heterozygosity for the variants C677T and A1298C within the MTHFR gene are related to NTDs in infants. Nonetheless, since now we have the very best worldwide frequency of homozygotes for the MTHFR C677T variant, we can not rule out that our propensity for NTDs could also be associated to how such gene variant interacts with different elements, primarily with our secular patterns of inappropriate folate consumption. This text is protected by copyright. All rights reserved.

Innovative Grade US Origin Bovine Fallopian Tube

IGBOFALS each
EUR 210
Description: Innovative Grade US Origin Bovine Fallopian Tube

Innovative Grade US Origin Bovine Fallopian Tube

IGBOFALZ each
EUR 133
Description: Innovative Grade US Origin Bovine Fallopian Tube

Normal Human Fallopian tube (single section per slide) (5 slides/pack)

HuFPT121 5 slides
EUR 150

Fallopian tube disease spectrum (fallopian tube cancer progression) tissue array

UTE601 each
EUR 306
Description: Fallopian tube disease spectrum (fallopian tube cancer progression) tissue array, including pathology grade, TNM and clinical stage, 30 cases/60 cores

Human Fallopian Tube Tissue Lysate

IHUFALTL100UG each
EUR 1413
Description: Human Fallopian Tube Tissue Lysate

Antibody Diluent for Frozen Sections

40125006-1 100 mL
EUR 42.29

Antibody Diluent for Frozen Sections

40125006-2 500 mL
EUR 91.14

Urogenital Tissue Slide (Fallopian Tube-Normal)

11-901-10um 10 um
EUR 241.8

Urogenital Tissue Slide (Fallopian Tube-Normal)

11-901-4um 4 um
EUR 216.6

Urogenital Tissue Slide (Fallopian Tube-Benign)

11-903-10um 10 um
EUR 241.8

Urogenital Tissue Slide (Fallopian Tube-Benign)

11-903-4um 4 um
EUR 216.6

cDNA - Human Adult Normal Tissue: Fallopian Tube

C1234115-10 10 reactions
EUR 215

Urogenital Tissue Slide (Fallopian Tube-Abnormal)

11-905-10um 10 um
EUR 241.8

Urogenital Tissue Slide (Fallopian Tube-Abnormal)

11-905-4um 4 um
EUR 216.6

cDNA - Monkey (Rhesus) Normal Tissue: Fallopian Tube

C1534115 40 reactions
EUR 578

Innovative Grade US Origin Porcine Fallopian Tube

IGPCFALF each
EUR 133
Description: Innovative Grade US Origin Porcine Fallopian Tube

Innovative Grade US Origin Porcine Fallopian Tube

IGPCFALP each
EUR 210
Description: Innovative Grade US Origin Porcine Fallopian Tube

Innovative Grade US Origin Porcine Fallopian Tube

IGPCFALS each
EUR 210
Description: Innovative Grade US Origin Porcine Fallopian Tube

Innovative Grade US Origin Porcine Fallopian Tube

IGPCFALZ each
EUR 133
Description: Innovative Grade US Origin Porcine Fallopian Tube

Total Protein - Human Adult Normal Tissue: Fallopian Tube

P1234115 1 mg
EUR 513

Human Urogenital Tissue Slide (Fallopian Tube normal) (5 slides/pk)

HTS-11901 1 pk
EUR 343.2

Human Urogenital Tissue Slide (Fallopian Tube Benign) (5 slides/pk)

HTS-11903 1 pk
EUR 343.2

Control sections for FD NeuroApop™ Kit (frozen)

PCS102- each
EUR 87.6

Control sections for FD NeuroApop™ Kit (frozen)

PCS102-2 each
EUR 80.54
Description: Best quality products

Human Urogenital Tissue Slide (Fallopian Tube Abnormal) (5 slides/pk)

HTS-11905 1 pk
EUR 343.2

Frozen Tissue Section - Asthma: Lung

T1236152Ld-1 5 slides
EUR 475

Frozen Tissue Section - Lupus: Ovary

T1236183Lup 5 slides
EUR 682

Frozen Tissue Section - Lupus: Kidney

T1236142Lup 5 slides
EUR 587

Frozen Tissue Section - Lupus: Spleen

T1236246Lup 5 slides
EUR 515

Frozen Tissue Section - Lupus: Adrenal

T1236004Lup 5 slides
EUR 515

Frozen Tissue Section - Emphysema: Lung

T1236152Ld-3 5 slides
EUR 475

Frozen Tissue Section - Pneumonia: Lung

T1236152Ld-4 5 slides
EUR 475

Frozen Tissue Section - Lupus: Pancreas

T1236188Lup 5 slides
EUR 515

Frozen Tissue Section - Bronchitis: Lung

T1236152Ld-2 5 slides
EUR 475

Frozen Tissue Section - Human Tumor: Bone

T1235023 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Lung

T1235152 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Skin

T1235218 5 slides
EUR 330

Frozen Tissue Section - hypertension: Vein

T1236020Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Tumor: Brain

T1235035 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Colon

T1235090 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Liver

T1235149 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Ovary

T1235183 5 slides
EUR 330

Frozen Tissue Section - Lupus: Spinal Cord

T1236234Lup 5 slides
EUR 515

Frozen Tissue Section - hypertension: Heart

T1236122Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Tumor: Breast

T1235086 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Kidney

T1235142 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Rectum

T1235206 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Testis

T1235260 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Uterus

T1235274 5 slides
EUR 330

Frozen Tissue Section - hypertension: Artery

T1236013Hd-2 5 slides
EUR 475

Frozen Tissue Section - hypertension: Kidney

T1236142Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Tumor: Adrenal

T1235004 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Bladder

T1235010 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Parotid

T1235190 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Stomach

T1235248 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Thymoma

T1235264 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Thyroid

T1235265 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Lymphoma

T1235161 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Pancreas

T1235188 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Prostate

T1235201 5 slides
EUR 330

Frozen Tissue Section - Human Tumor: Esophagus

T1235106 5 slides
EUR 330

Frozen Tissue Section - Arteriosclerosis: Aorta

T1236012Hd-4 5 slides
EUR 1060

Frozen Tissue Section - Arteriosclerosis: Artery

T1236013Hd-4 5 slides
EUR 1060

Frozen Tissue Section - Human Adult Normal: Lung

T1234152 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Skin

T1234218 5 slides
EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain

T1236035Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain

T1236035Par 5 slides
EUR 475

Frozen Tissue Section - Dementia: Brain: Thalamus

T1236079Dem 5 slides
EUR 475

Frozen Tissue Section - Lupus: Heart: Pericardium

T1236133Lup 5 slides
EUR 515

Frozen Tissue Section - Pulmonary embolism: Lung

T1236152Ld-5 5 slides
EUR 475

TUNEL in situ cell apoptosis detection kit, frozen section

EBA23100 100 assays
EUR 700

TUNEL in situ cell apoptosis detection kit, frozen section

EBA2320 20 assays
EUR 250

TUNEL in situ cell apoptosis detection kit, frozen section

EBA2350 50 assays
EUR 440

Frozen Tissue Section - Human Adult Normal: Brain

T1234035 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Colon

T1234090 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Heart

T1234122 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Liver

T1234149 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Ovary

T1234183 5 slides
EUR 629

Frozen Tissue Section - Human Adult Normal: Penis

T1234194 5 slides
EUR 343

Frozen Tissue Section - Arrhythmia, infarct: Heart

T1236122Hd-1 5 slides
EUR 475

Frozen Tissue Section - Liver Cirrhosis: Prostate

T1236201Lcs 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Breast

T1234086 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Retina

T1234110 5 slides
EUR 529

Frozen Tissue Section - Human Adult Normal: Kidney

T1234142 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Rectum

T1234206 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Spleen

T1234246 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Testis

T1234260 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Throat

T1234263 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Uterus

T1234274 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Vagina

T1234283 5 slides
EUR 343

Frozen Tissue Section - Lupus: Blood Vessel: Artery

T1236013Lup 5 slides
EUR 515

Frozen Tissue Section - Depression: Brain: Thalamus

T1236079Dep 5 slides
EUR 475

Frozen Tissue Section - Liver Cirrhosis: Esophagus

T1236106Lcs 5 slides
EUR 475

Frozen Tissue Section - Dementia: Brain: Frontal Lobe

T1236051Dem 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Adipose

T1234003 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Adrenal

T1234004 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Bladder

T1234010 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Trachea

T1234160 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Parotid

T1234190 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Stomach

T1234248 5 slides
EUR 343

Frozen Tissue Section - Dementia: Brain: Hippocampus

T1236052Dem 5 slides
EUR 883

Frozen Tissue Section - Human Adult Normal: Appendix

T1234006 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Pancreas

T1234188 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Placenta

T1234200 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Prostate

T1234201 5 slides
EUR 343

Frozen Tissue Section - Depression: Brain: Frontal Lobe

T1236051Dep 5 slides
EUR 475

Frozen Tissue Section - Depression: Brain: Hippocampus

T1236052Dep 5 slides
EUR 883

Frozen Tissue Section - Human Adult Normal: Esophagus

T1234106 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Diaphragm

T1234169 5 slides
EUR 343

Frozen Tissue Section - Dementia: Brain: Parietal Lobe

T1236066Dem 5 slides
EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Pons

T1236071Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Pons

T1236071Par 5 slides
EUR 475

Frozen Tissue Section - Dementia: Brain: Temporal Lobe

T1236078Dem 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Pons

T1234071 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Lymph Node

T1234161 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Epididymis

T1234105 5 slides
EUR 343

Frozen Tissue Section - Dementia: Brain: Occipital Lobe

T1236062Dem 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Spinal Cord

T1234234 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Gallbladder

T1234118 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Parathyroid

T1234189 5 slides
EUR 758

Frozen Tissue Section - Depression: Brain: Parietal Lobe

T1236066Dep 5 slides
EUR 475

Frozen Tissue Section - Depression: Brain: Temporal Lobe

T1236078Dep 5 slides
EUR 475

Frozen Tissue Section - Congenital heart disease: Heart

T1236122Hd-3 5 slides
EUR 475

Frozen Tissue Section - Congestive Heart Failure: Heart

T1236122Hd-6 5 slides
EUR 794

Frozen Tissue Section - hypertension: Heart Atrium, left

T1236126Hd-2 5 slides
EUR 475

Frozen Tissue Section - Depression: Brain: Occipital Lobe

T1236062Dep 5 slides
EUR 475

Frozen Tissue Section - hypertension: Heart Atrium, right

T1236127Hd-2 5 slides
EUR 475

Frozen Tissue Section - Multiple Sclerosis Disease: Brain

T1236035Msc 5 slides
EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Amygdala

T1236036Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Amygdala

T1236036Par 5 slides
EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Thalamus

T1236079Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Thalamus

T1236079Par 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Amygdala

T1234036 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Midbrain

T1234059 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Thalamus

T1234079 5 slides
EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Pituitary

T1236068Alz 5 slides
EUR 883

Frozen Tissue Section - Parkinson's Disease: Brain: Pituitary

T1236068Par 5 slides
EUR 883

Frozen Tissue Section - hypertension: Heart Ventricle, left

T1236138Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Ductus Deferens

T1234100 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Skeletal Muscle

T1234171 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Small Intestine

T1234226 5 slides
EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Eye

T1236108Dia 5 slides
EUR 662

TUNEL in situ cell apoptosis detection kit, fluorescence, frozen section

EBA27100 100 assays
EUR 700

TUNEL in situ cell apoptosis detection kit, fluorescence, frozen section

EBA2720 20 assays
EUR 250

TUNEL in situ cell apoptosis detection kit, fluorescence, frozen section)

EBA2750 50 assays
EUR 440

Frozen Tissue Section - Alzheimer's Disease: Brain: Cerebellum

T1236039Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Cerebellum

T1236039Par 5 slides
EUR 475

Frozen Tissue Section - hypertension: Heart Ventricle, right

T1236139Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Brain Stem

T1234075 5 slides
EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Frontal Lobe

T1236051Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Frontal Lobe

T1236051Par 5 slides
EUR 475

Frozen Tissue Section - hypertension: Interventricular Septum

T1236130Hd-2 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Cerebellum

T1234039 5 slides
EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Lung

T1236152Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Skin

T1236218Dia 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Brain: Frontal Lobe

T1234051 5 slides
EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Hippocampus

T1236052Alz 5 slides
EUR 883

Frozen Tissue Section - Human Adult Normal: Blood Vessel: Vein

T1234020 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Optic Nerve

T1234064 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Heart: Atrium (left)

T1234126 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Hippocampus

T1234052 5 slides
EUR 758

Frozen Tissue Section - Human Adult Normal: Heart: Pericardium

T1234133 5 slides
EUR 343

Frozen Tissue Section - Human Diabetic Diseased Tissue: Brain

T1236035Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Colon

T1236090Dia 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Heart

T1236122Dia 5 slides
EUR 475

Frozen Tissue Section - Arrhythmia, infarct: Heart Atrium, left

T1236126Hd-1 5 slides
EUR 475

Frozen Tissue Section - Human Diabetic Diseased Tissue: Liver

T1236149Dia 5 slides
EUR 475

Frozen Tissue Section - Human Adult Normal: Heart: Arcus Aortae

T1234124 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Heart: Atrium (right)

T1234127 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Brain: Diencephalon

T1234049 5 slides
EUR 343

Frozen Tissue Section - Human Adult Normal: Submaxillary Gland

T1234165 5 slides
EUR 343

Frozen Tissue Section - Alzheimer's Disease: Brain: Parietal Lobe

T1236066Alz 5 slides
EUR 475

Frozen Tissue Section - Parkinson's Disease: Brain: Parietal Lobe

T1236066Par 5 slides
EUR 475

Frozen Tissue Section - Multiple Sclerosis Disease: Brain: Pons

T1236071Msc 5 slides
EUR 475

Frozen Tissue Section - Alzheimer's Disease: Brain: Temporal Lobe

T1236078Alz 5 slides
EUR 475

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